Police are making inquiries after receiving a report of a vehicle allegedly being driven toward protestors in central Dunedin

Anti-vaccine and anti-mandate protestors blocked the main street, as they paraded towards the Octagon on Saturday.

The Hits' Dunedin radio host Callum Proctor says the incident apparently happened at the intersection of St Andrew and George Streets.

He says the road wasn't cordoned off to stop traffic.

Police are also investigating a Dunedin woman who's posted a threatening video on social media, apposing children getting vaccinated.